Midlife Obesity Increases Alzheimer's Risk, April 4, 2006

Individuals over 40 who are overweight have an increased risk of developing Alzheimer's disease.

Scientists followed nearly 9,000 people for up to 30 years who were evaluated for overweight and obesity by measuring upper arm and shoulder skinfold thickness.

Those their 40s who were overweight were more likely to develop Alzheimer's disease than those with smaller measurements.

People who were the most overweight were nearly three times as likely to develop Alzheimer's disease.

"These findings are important because obesity and overweight are treatable and modifiable risk factors," said study author Rachel Whitmer. "These results need to be confirmed, but (they) suggest that keeping your weight down in midlife can help you remain mentally alert later on in life."

The study was presented Wednesday during the American Academy of Neurology's 58th Annual Meeting in San Diego.